Figure 6.

Characteristic time course of an early airway response in an anesthetized, orotracheally intubated Brown Norway rat during and after inhalational challenge with ovalbumin. Marked increase in lung resistance (R_L) is shown and a decrease in dynamic compliance (C_dyn) is paralleled by decreases in lung conductance (G_L), midexpiratory flow (EF₅₀) and tidal volume (V_T). Also a slight increase in respiratory frequency (f) was observed. The x-axis represents the experimental time (unit = 1 min).