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Development of respiratory parameters in non-anesthetized juvenile Wistar rats. (A) Tidal volume; (B) tidal midexpiratory flow; *p < 0.05 male vs. female; mean values ± SEM, measured values of n = 8/sex (except males on post-natal day (PND) seven and females on PND 21 and 45: n = 7). Closed symbols represent male animals (♦) and open symbols represent female animals (○). [reprinted with permission from Lewin et al. (2010)]; see there for additional data).
