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. 2012 Jan 16;55(4):1511–1525. doi: 10.1021/jm201195m

Figure 4.

Figure 4

Craig plot for aromatic substituents of σ vs π. π is the substituent hydrophobicity constant and σ the Hammett substitution constant, a measure of the electronic influence of the substituent. Values were obtained from model systems from refs (30), (56), and (57).