Table 7.
Univariate logistic regression analysis of clinical and histopathological predictors of microsatellite instability
| Variable | Odds ratio | 95% confidence interval | P |
|---|---|---|---|
| Male sex |
2.59 |
0.8-8.2 |
0.125 |
| Age less than 60 years |
1.74 |
0.4-3.6 |
0.344 |
|
Right-sided CRC |
8.5 |
2.7-26.7 |
0.001 |
| Poor and well differentiation |
2.18 |
0.8-7.3 |
0.181 |
|
Any mucinous differentiation |
3.272 |
1.2-8.7 |
0.040 |
| TIL>5/HPF |
2.21 |
0.8-5.4 |
0.158 |
| Lower disease stage (UICC stage; I and II) |
1.06 |
0.3-2 |
0.918 |
| Any BGrev criterion fulfillment | 6.99 | 2.5-19.9 | 0.001 |
*Abbreviations: CRC – colorectal cancer; TIL – tumor infiltrating lymphocytes; HPF – high-powered field; UICC – Union for International Cancer Control staging; BGrev – Revised Bethesda guidelines.