Table 2. Immunological and virological characteristics and HAART type, by treatment sub-group.
HAART type at conception |
First antenatal CD4 count Median (IQR) cells/mm3 |
First antenatal HIV RNA Median (IQR) log10 copies/ml |
Timing of first antenatal measurement Median (IQR) Gest weeks |
Gestational age at interruption or switch Median (IQR) |
N (%) with undetectable HIV RNA levels in 4 weeks up to delivery |
||
---|---|---|---|---|---|---|---|
|
|
||||||
PI-based N (%) |
NNRTI- based N (%) |
||||||
No change to regimen n=72 |
49 (68) | 23 (32) | 421 (304-560) |
2.77 (2.44-3.65) |
12 (8-22) | N/A | 24/60 (40) |
Interruption of HAART n=31 |
14 (45) | 17 (55) | 360 (270-412) |
4.08 (3.37-4.45) |
12 (9-16) | 7 weeks (5-8) | 10/24 (42) |
Switch to new regimen n=24 |
15 (63) | 9 (38) | 306 (208-447) |
3.12 (2.91-3.48) |
10 (6-16) | 21 weeks (15-24) | 5/19 (26) |