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. Author manuscript; available in PMC: 2012 Aug 28.
Published in final edited form as: Diabetologia. 2010 Jul 8;53(10):2134–2138. doi: 10.1007/s00125-010-1847-0

Table 2.

Association between maternal gestational diabetes mellitus status and children’s cognitive test scores

n=515 (whole cohort)
Cognitive tests ODM (n=32)
Mean (SD)
Controls (n=483)
Mean (SD)
P b β (95% CI) P c β (95% CI) P d β (95% CI) P e
Learning, long-term
retrieval/storage
(Atlantis)
75.9 (16.2) 67.5 (17.1) 0.008 0.5(0.12,0.84) 0.009 0.4(0.02,0.71) 0.04 0.4(0.01,0.75) 0.04
Short-term memory
(Word order)
17.0 (2.7) 16.4 (2.6) 0.2 0.2(−0.19, 0.54) 0.3 0.02(−0.33,0.37) 0.9 0.03(−0.35,0.40) 0.8
Reasoning ability a
(Pattern reasoning)
12.5 (9.0, 16.0) 10.0 (4.0, 14.0) 0.02 0.4(0.01,0.73) 0.04 0.2(−0.10,0.58) 0.2 0.1(−0.23,0.51) 0.4
Verbal ability-animals
(Verbal fluency)
13.1 (3.0) 12.0 (3.3) 0.07 0.3(−0.05,0.67) 0.09 0.2(−0.12,0.59) 0.2 0.2(−0.16,0.61) 0.2
Verbal ability-names
(Verbal fluency)
18.2 (5.2) 16.0 (4.9) 0.01 0.4(0.01,0.71) 0.04 0.3(−0.05,0.64) 0.09 0.5(0.09,0.83) 0.02
Visuo-spatial ability a
(Koh’s block design)
85.3 (68.1, 97.3) 76.2 (62.6, 87.8) 0.1 0.3(−0.06,0.66) 0.1 0.2(−0.18,0.52) 0.4 0.01(−0.36,0.39) 0.9
Attention and concentration
(Coding-WISC-III)
36.8 (8.0) 32.4 (8.1) 0.003 0.4(0.09,0.75) 0.01 0.3(0.01,0.67) 0.04 0.3(−0.04,0.67) 0.08
a

Transformed variable; values are median (Inter-quartile range).

b

P values are for the difference between ODM’s and controls derived using t-tests

β is the effect size (SD) on the outcome (non transformed and transformed) per unit change in the exposure (maternal gestational diabetes mellitus status) derived using multiple linear regression.

c

P value derived using multiple linear regression adjusted for child’s sex, gestation and age

d

P value derived using multiple linear regression adjusted for child’s sex, gestation, age, SES, parents’ education and rural/urban residence

e

P value derived using multiple linear regression adjusted for child’s sex, gestation, age, SES, parents’ education, rural/urban residence, maternal age, BMI and parity in pregnancy and child’s weight and head circumference at birth.