Table 2.
Independent variables | Base | Crude OR (95% C.I.) |
Crude p value |
Adjusted OR (95% C.I.) |
Adjusted p value |
---|---|---|---|---|---|
Mother’s marital status | |||||
Married or cohabiting | 3894 | 1 | 1 | ||
Single, divorced, separated or widowed | 865 | 6.35 (4.23,9.54) | p≤0.001 | 4.08 (2.60,6.40) | p≤0.001 |
Mother’s age at leaving full- atime education |
|||||
≤16 years | 539 | 1 | 1 | ||
17-18 years | 727 | 0.50 (0.29,0.89) | p=0.019 | 0.61 (0.32,1.18) | p=0.142 |
≥19 years | 1192 | 0.13 (0.06,0.27) | p≤0.001 | 0.23 (0.10,0.52) | p≤0.001 |
Missing | 2301 | 0.28 (0.17,0.46) | p≤0.001 | 0.37 (0.21,0.65) | p≤0.001 |
Maternal IDU history | |||||
No | 3895 | 1 | -- | -- | |
Yes | 884 | 4.46 (2.98,6.67) | p≤0.001 | ||
Mother a partner of IDU | |||||
No | 3214 | 1 | -- | -- | |
Yes | 1565 | 1.56 (1.04,2.34) | p=0.031 | ||
Timing of maternal HIV diagnosis | |||||
Before pregnancy | 1455 | 1 | |||
1st/2nd trimester | 2271 | 0.12 (0.06,0.25) | p≤0.001 | -- | -- |
3rd trimester /delivery | 1033 | 1.33 (0.87,2.03) | p=0.187 | ||
ARV prophylaxis | |||||
sdNVP only | 549 | 1 | 1 | ||
None | 395 | 1.64 (1.04,2.58) | p=0.032 | 1.34 (0.82,2.18) | p=0.244 |
Antenatal prophylaxis +/− sdNVP | 3815 | 0.05 (0.03,0.09) | p≤0.001 | 0.12 (0.06,0.23) | p≤0.001 |
Mode of delivery | |||||
Vaginal | 2962 | 1 | 1 | ||
Elective CS | 1590 | 0.08 (0.03,0.21) | p≤0.001 | 0.37 (0.13,1.08) | p=0.069 |
Emergency CS | 207 | 0.15 (0.02,1.08) | p=0.060 | 0.20 (0.03,1.54) | p=0.122 |
Birth order of infant | |||||
Firstborn | 2882 | 1 | 1 | ||
Second born | 1409 | 2.90 (1.82,4.61) | p≤0.001 | 1.89 (1.14,3.13) | p=0.014 |
≥ Third born | 468 | 4.97 (2.89,8.55) | p≤0.001 | 2.56 (1.41,4.65) | p=0.002 |
Gestational age of infant | |||||
≥37 weeks | 4342 | 1 | 1 | ||
34-36 weeks | 291 | 3.60 (2.06,6.29) | p≤0.001 | 1.79 (0.97,3.30) | p=0.064 |
<34 weeks | 126 | 7.12 (3.83,13.26) | p≤0.001 | 3.40 (1.67,6.92) | p=0.001 |
Birthweight of infant | |||||
≥2500g | 4165 | 1 | -- | -- | |
<2500g | 594 | 3.71 (2.42,5.69) | p≤0.001 | ||
NAS in infant | p≤0.001 | ||||
No | 4640 | 1 | 1 | ||
Yes | 119 | 10.97 (6.40,18.80) | p≤0.001 | 3.27 (1.76,6.09) | p≤0.001 |