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. Author manuscript; available in PMC: 2012 Aug 28.
Published in final edited form as: Leukemia. 2008 May 29;22(8):1595–1603. doi: 10.1038/leu.2008.129

Figure 5. Induction of IL-22R1 expression in NPM-ALK activated cell line.

Figure 5

Figure 5

A) RT-PCR studies confirmed the expression of NPM-ALK in Jurkat cells after transfection. Jurkat cells transfected with an empty vector was included as a negative control.

B) Transfection of Jurkat cells with NPM-ALK induced expression of IL-22R1 detectable by Western blots. After stimulation with IL-22 recombinant protein, pSTAT3 levels were detected in Jurkat cells transfected with NPM-ALK, but not in cells transfected with an empty vector.