Table 4.
Diplotype Frequencies and Associations Between Spontaneous Recovery and Chronic Liver Disease in GNLY Haplotypes
| |
|
Frequency (%) |
|
SR vs CLD |
|
|
|
|||
|---|---|---|---|---|---|---|---|---|---|---|
| SNP | Diplotype | SR | CLD | Model | OR | Lower CI | Upper CI | pa | pb | pc |
| HT1 | HT1/HT1 | 28 (8.95) | 73 (23.32) | Additive | 1.03 | 0.73 | 1.46 | 0.854 | ||
| C-G-T | HT1/- | 67 (21.41) | 90 (28.75) | Dominant | 0.65 | 0.38 | 1.10 | 0.109 | ||
| -/- | 12 (3.83) | 43 (13.74) | Recessive | 2.23 | 1.11 | 4.48 | 0.025 | 0.035 | 0.123 | |
| HT2 | HT2/HT2 | 5 (1.6) | 31 (9.9) | Additive | 0.99 | 0.68 | 1.43 | 0.953 | ||
| T-C-C | HT2/- | 69 (22.04) | 92 (29.39) | Dominant | 0.26 | 0.10 | 0.71 | 0.008 | 0.011 | 0.042 |
| -/- | 33 (10.54) | 83 (26.52) | Recessive | 1.57 | 0.95 | 2.61 | 0.080 | |||
The CI and pa values were obtained from logistic regression with additive, dominant, and recessive models.
The pb values were calculated by the permutation test.
The pc values were calculated by Bonferroni's correction.