Table 1.
Variable | Obese (n=273) | Nonobese (n=222) | P | IR (n=117) | Non-IR (n=368) | P |
---|---|---|---|---|---|---|
Age (years) | 38.4±9.1 | 40.8±8.3 | 0.003a | 39.6±8.9 | 39.2±8.5 | 0.6 |
Body mass index (kg/m2) | 28.6±2.8 | 21.5±2.3 | 0.01a | 27.3±4.2 | 24±4.1 | 0.001a |
Waist circumference (cm) | 93.7±9.8 | 81.0±10.5 | 0.001a | 91.6±10.5 | 85.0±12.2 | 0.001a |
Hip circumference (cm) | 101.5±7.9 | 90.2±7.8 | 0.001a | 99.5±7.8 | 93.7±9.7 | 0.001a |
Waist–hip ratio | 0.91±0.06 | 0.89±0.09 | 0.004a | 0.90±0.1 | 0.90±0.2 | 0.5 |
Skinfold thickness (mm) | ||||||
Biceps | 20.7±8.5 | 14.5±7.7 | 0.001a | 21.3±8.1 | 16.0±5.2 | 0.001a |
Triceps | 28.2±9.6 | 20.5±7.9 | 0.001a | 27.5±8.5 | 22.7±9.2 | 0.001a |
Subscapular | 35.8±7.7 | 27.1±7.9 | 0.001a | 35.2±7.9 | 29.5±8.8 | 0.001a |
Suprailiac | 39.7±7.7 | 27.8±9.2 | 0.001a | 41.6±7.2 | 30.4±10.6 | 0.001a |
Total | 119.7±26.9 | 90±27.1 | 0.001a | 120.4±24.3 | 97.2±21.2 | 0.001a |
FPG (mmol/L) | 5.2±1.3 | 5.0±0.7 | 0.2 | 5.1±1.0 | 5.0±0.9 | 0.4 |
Triglycerides (mmol/L) | 9.2±2.4 | 7.0±2.9 | 0.001a | 9.1±2.6 | 7.1±2.9 | 0.001a |
Total cholesterol (mmol/L) | 10.6±2.1 | 9.9±2.7 | 0.001a | 11.1±2.2 | 10±2.3 | 0.008a |
LDL-C (mmol/L) | 6.4±1.9 | 6.1±2.0 | 0.1 | 6.5±1.6 | 5.6±1.2 | 0.2 |
HDL-C (mmol/L) | 2.3±0.6 | 2.3±0.6 | 0.5 | 2.3±0.5 | 2.6±0.8 | 0.5 |
VLDL (mmol/L) | 1.8±0.6 | 1.43±0.5 | 0.04a | 1.8±0.9 | 1.5±0.8 | 0.01a |
Serum leptin (μg/L) | 28.1 (0.4–98.3)b | 10.8 (0.3–61.2)b | 0.001a | 24±7.2 | 17.2±6.2 | 0.002a |
Serum adiponectin (ng/L) | 26.8±9.5 | 34.8±9.2 | 0.02a | 26.2±8.9 | 32.1±9.2 | 0.005a |
Fasting insulin (μU/L)b | 9.9 (0.3–41.2) | 6.5 (0.2–52.3) | 0.001a | 15.5 (1.2–63.4) | 5.7 (0.5–41.6) | 0.001a |
HOMA-IRb | 3.2 (0.1–9.7) | 1.3 (0–12.1) | 0.001a | 3.5 (0.1–11.7) | 1.2 (0.1–9.9) | 0.003a |
Data are mean±SD values for the indicated number of subjects (n) unless indicated otherwise.
Significant difference.
Median (minimum – maximum).
FPG, fasting plasma glucose; HDL-C, high-density lipoprotein cholesterol; HOMA, homoeostasis model assessment for insulin resistance; IR, insulin resistance; LDL-C, low-density lipoprotein cholesterol; VLDL, very low-density lipoprotein.