Table 3.
Association of the Peroxisome Proliferator-Activated Receptor γ2 Pro12Ala Genotype with Obesity and Insulin Resistance
| Parameter | Pro/Pro | Pro/Ala | Ala/Ala | P |
|---|---|---|---|---|
| BMI odds ratio (95% CI) | ||||
| Unadjusted | 1.0 | 1.4 (0.8–2.3) | 4.4 (1.2–16.4) | 0.02a |
| Adjusted | 1.0 | 1.3 (0.8–2.1) | 3.2 (1.2–12.9) | |
| IR odds ratio (95% CI) | ||||
| Unadjusted | 1.0 | 0.93 (0.5–1.7) | 3.8 (1.24–11.5) | 0.01a |
| Adjusted | 1.0 | 0.82 (0.4–1.63) | 3.6 (1.04–12.4) | 0.04a |
Pro/Pro, Pro/Ala, and Ala/Ala genotypes are expressed as the representative baseline with 95% class interval (CI). Body mass index (BMI) was adjusted for age, gender, and fasting insulin; insulin resistance (IR) was adjusted for age, gender, triglycerides, and waist circumference).
a
Significant difference.