Skip to main content
. Author manuscript; available in PMC: 2013 Mar 19.
Published in final edited form as: Chembiochem. 2012 Feb 14;13(5):665–673. doi: 10.1002/cbic.201100763

Figure 4. IR-dependent activation of Abl kinase in murine v-Abl-expressing pre-B ATM (−/−) null cells is sensitive to a DNAPK inhibitor.

Figure 4

The biosensor assay was performed with v-Abl transfected preB cells that were A) WT or B) deficient for ATM expression. C) Data over two independent experiments were averaged and plotted. Statistically significant differences (p<0.05) between ATM (WT) and ATM (null) are indicated via *. Y-axis is labelled as norm increase (+IR), meaning the increase in the 4G10/strept signal for samples treated with IR vs non-IR controls. Error bars represent SEM.