Table 2.

Substrate Scope of the Intramolecular Amination of Allylic Alcohols (0.6 M) Catalyzed by a 1:2 Mixture of [(S)-2](AuCl)₂ (2.5 mol %) and AgClO₄ (5 mol %) in Dioxane at 25 °C for 48 h.^[18]

entry	substrate	heterocycle	yield [%][a]	ee [%][b]
1	(Z)-1g	3g	95	Š5
2	(R = Me)		94	90
3	[R-R = –(CH2)5–]		95	94
4			89	62
5	4 (R = Ph)	5	87[c]	90/92
6	(R = i-Pr)		98[c]	85/91
7			87[c]	88/90
8			69	77
9[d]	(R1 = Fmoc, R2 = Boc)		86	94
10[d]	(R1 = Fmoc, R2 = Ts)		99	92
11[d]	(R1 = Boc, R2 = Fmoc)		99	91

^[a]Isolated yield.

^[b]Determined by HPLC analysis on chiral support.

^[c]Diastereomeric ratio = ~1:1.

^[d]Reaction run at 50 °C.