Table 5.

MIC and IC₅₀ values for selected compounds isolated from and Westiellopsis sp. (SAG 20.93) and Fischerella muscicola (UTEX LB1829)

	MIC (μM)						IC50 (μM)
	M. tuberculosis a	M. smegmatis b	C. albicans c	S. aureus d	E. coli e	A. baumanii f	Vero
Hapalindole X (1)	2.5	78.8	2.5	9.1	> 100	> 100	35.2
Deschloro hapalindole I (2)	> 100	> 100	> 100	> 100	> 100	> 100	> 100
13-hydroxy dechlorofontonamide (3)	> 100	> 100	> 100	> 100	> 100	> 100	> 100
Hapalindole I	2.0	> 100	> 100	> 100	> 100	> 100	> 100
Hapalindole J	4.3	39.0	0.7	8.4	> 100	> 100	31.9
Hapalindole A	< 0.6	18.2	1.2	3.9	8.0	> 100	25.6
Anhydrohapaloxindole A	16.2	>100	1.9	27.3	> 100	> 100	79.9
Hapalonamide H	1.2	34.3	< 0.6	> 100	> 100	> 100	13.6
Fischerindole L	22.0	63.0	1.2	6.4	> 100	> 100	< 9.2
Fischerellin A	43.1	>100	> 100	> 100	> 100	> 100	94.8
Fischerellin B	23.0	>100	> 100	> 100	> 100	> 100	> 100
Rifampin	0.24
Streptomycin		0.41
Amphotericin B			0.12
Ampicillin				1.54
Gentamycin					2.3
Doxycycline						0.35

^aMycobacterium tuberculosis.

^bMycobacterium smegmatis.

^cCandida albicans.

^dStaphylococcus aureus.

^eEscherichia coli.

^fAcinetobacter baumannii.