Table 1. Correlation between volepox virus infection and immune response.

Animal ID	Necropsy *	Cause of death	Inoculum	Lesions or signs of disease	ELISA **	Western Blot ***
PC 007	Day 6	D	VPXV 1.6 e3	paw, tongue, vulvae, liver	POS	18
PC 011	Day 6	D	VPXV 1.6 e3	conjuntivitis, vulvae, tongue	NEG	36,18
PC 012	Day 6	E	VPXV 1.6 e3	intestine, ovaries	POS	36,18
PC 014	Day 6	D	VPXV 1.6 e3	tail, tongue	POS	62,36,21
PC 020	Day 6	E	VPXV 1.6 e3	tongue, lip, nose	NEG	62,36,21
PC 030	Day 6	E	VPXV 1.6 e3	tail, tongue	POS	18
PC 008	Day 7	E	VPXV 1.6 e3	liver	NEG	36
PC 018	Day 7	E	VPXV 1.6 e3	tongue, intestine	NEG	62
PC 024	Day 7	D	VPXV 1.6 e3	paw, eyelid, intestine, liver	NEG	NEG
PC 027	Day 7	D	VPXV 1.6 e3	ear, tongue, intestine, kidney	NEG	NEG
PC 034	Day 7	E	VPXV 1.6 e3	submandibular lymph node	POS	62,36,21
PC 022	Day 8	D	VPXV 1.6 e3	lip, adrenal gland	POS	39,36,18
PC 037	Day 8	D	VPXV 1.6 e3	none	POS	62,21,18
PC 015	Day 21	S	VPXV 1.6 e3	skin	POS	62,36,25,21,14,11
PC 009	Day 35	S	VPXV 1.6 e3	skin	POS	62,36,14
PC 013	Day 35	S	VPXV 1.6 e3	tail	POS	62,36,14
PC 010	Day 42	S	VPXV 1.6 e3	skin	NEG	NEG
PC 016	Day 42	S	VPXV 1.6 e3	eyelid	POS	62,32,14
PC 021	Day 42	S	VPXV 1.6 e3	skin	POS	62,25,21,18,14,11
PC 017	Day 49	S	VPXV 1.6 e3	tail	NEG	NEG
PC 023	Day 49	S	VPXV 1.6 e3	tail	POS	75,62,36,32,25,21,18,14
PC 029	Day 49	S	VPXV 1.6 e3	tail	POS	62,36,14,11
PC 026	Day 56	S	VPXV 1.6 e3	crusty nose	POS	25,21,18,14
PC 032	Day 56	S	VPXV 1.6 e3	none	POS	62,36,14
PC 038	Day 7	S	PBS	none	NEG	NEG
PC 039	Day 14	S	PBS	none	NEG	NEG
PC 040	Day 21	S	PBS	none	NEG	NEG
PC 041	Day 28	S	PBS	none	NEG	NEG
PC 061	Day 35	S	PBS	none	NEG	NEG
PC 074	Day 42	S	PBS	none	NEG	NEG
PC 081	Day 49	S	PBS	none	NEG	NEG

^*Days post infection.

^**POS, positive.NEG, negative.

^***Protein band observed, size in kDa. NEG, no band observed.

D, die due to infection. E, met the euthanasia criteria. S, study scheduled euthanasia.