Table 1. Bone mineral density, microarchitecture of the trabecular and cortical bone at the femur diaphysis after a bone animal experiment on chronic alcohol consumption.
C (n = 11) | A25 (n = 8) | A35 (n = 8) | p | |
WB BMD (g/cm2) | 0,207±0,004 | 0,194±0,005c | 0,189±0,006c | p<0,0001 |
Femur BMD(g/cm2) | 0,394±0,013 | 0,354±0,010c | 0,335±0,020c,a | p<0,0001 |
BV/TV (%) | 16,09±5,49 | 13,83±3,73 | 12,09±2,64 | NS |
Tb.Th (mm) | 0,095±0,011 | 0,083±0,005c | 0,085±0,009 | 0,03 |
Ct.Po (%) | 1,03±0,28 | 1,15±0,32 | 1,42±0,35c | 0,01 |
Po.N (1/mm) | 0,24±0,05 | 0,29±0,07 | 0,35±0,08c | 0,008 |
PoS/CtV(mm2/mm3) | 1.63±0.17 | 1.91±0.34 | 2.24±0.54c | 0,002 |
The alcohol-fed rats (A25, A35) drank alcohol for 17 weeks (25% and 35% v/v) while the control group (C) drank water. The critical p-value (p) was 0.05;
significant according to controls,
significant according to A25 group. Data were expressed as mean ± standard deviation (sd).