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. 2012 Aug 28;7(8):e43930. doi: 10.1371/journal.pone.0043930

Table 1. Bone mineral density, microarchitecture of the trabecular and cortical bone at the femur diaphysis after a bone animal experiment on chronic alcohol consumption.

C (n = 11) A25 (n = 8) A35 (n = 8) p
WB BMD (g/cm2) 0,207±0,004 0,194±0,005c 0,189±0,006c p<0,0001
Femur BMD(g/cm2) 0,394±0,013 0,354±0,010c 0,335±0,020c,a p<0,0001
BV/TV (%) 16,09±5,49 13,83±3,73 12,09±2,64 NS
Tb.Th (mm) 0,095±0,011 0,083±0,005c 0,085±0,009 0,03
Ct.Po (%) 1,03±0,28 1,15±0,32 1,42±0,35c 0,01
Po.N (1/mm) 0,24±0,05 0,29±0,07 0,35±0,08c 0,008
PoS/CtV(mm2/mm3) 1.63±0.17 1.91±0.34 2.24±0.54c 0,002

The alcohol-fed rats (A25, A35) drank alcohol for 17 weeks (25% and 35% v/v) while the control group (C) drank water. The critical p-value (p) was 0.05;

c

significant according to controls,

a

significant according to A25 group. Data were expressed as mean ± standard deviation (sd).