Table 1. Demographic data of the study population.
sham (n = 8) | dxm (n = 7) | rof (n = 7) | |
Median age [years] | 4.0±0.6 | 3.9±0.3 | 4.4±0.1 |
Body weight [g] | 440±51 | 409±25 | 429±57 |
Sex, n | |||
Male | 4 | 3 | 2 |
Female | 4 | 4 | 5 |
Animal number | #13901 a | #13958 a | #13859 a |
#14374 a | #13763 a | #13866 a | |
#13952 a | #13853 a | #13605 a | |
#14168 a | #14168 b | #13763 b | |
#14299 a | #13866 b | #13863 b | |
#13859 b | #13853 b | #13958 b | |
#14374 b | #12785 b | #11595 b | |
#13564 b | |||
Excluded | #13605 b | #13863 a | #13526 a |
Animals were randomized in each of the two independent study cycles as indicated (a: first study cycle, b: second study cycle). Before each cycle a baseline BAL was performed 3 weeks before LPS challenge and served as control. Altogether, 3 animals had to be excluded.
Data are given as mean ± S.E.M., dxm = dexamethasone, rof = roflumilast.