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. 2012 Aug 28;7(8):e43580. doi: 10.1371/journal.pone.0043580

Figure 6. The effects of hit compounds on LRRK2 phosphorylation at serines 910, 935, 955 and 973.

Figure 6

Flp-In T-REx™ HEK293 GFP-LRRK2 G2019S cells (GS) or A2016T/G2019S (IRM) were induced and treated with indicated compounds at 20 µM. After cell lysis, GFP-LRRK2 was immunoprecipitated and the phosphorylation of LRRK2 was analyzed by immunoblotting. The quantifications are from 3 independent experiments.