Figure 3. Thymocyte populations in M-MuLV infected mice. A) Flow cytometry analysis of thymi from control and M-MuLV infected mice. Cells were stained with anti-CD4 and anti-CD8 antibodies to distinguish CD4^-/CD8^- (DN), CD4⁺/CD8⁺ (DP), CD4⁺/CD8^- (CD4⁺) and CD4^-/CD8⁺ (CD8⁺) populations. B) Percentages of DN, DP, CD4⁺ and CD8⁺ from representative populations of mice (Vav1^+/+ control (n = 6); Vav1^−/− control (n = 6); Vav1^+/+ M-MuLV (n = 4); Vav1^−/− M-MuLV (n = 9)). The numbers in brackets reflect the mice whose plots are depicted in panel A. C) Representative histograms showing TCRβ expression in the CD4⁺/CD8^- subset of different mice populations. Data were evaluated using Student’s t-test: * p < 0.05; **p < 0.01; ***p < 0.001.