Table 2. The list of FUS-regulated exons with proximal crosslink clusters of FUS. The genomic positions of the exons are shown, as well as the number of FUS, TDP-43 or U2AF65 crosslink sites in crosslink clusters located within 250nt from the middle of the exon. Crosslink clusters were determined using flank = 200 and FDR<0.05.
cross-linking sites | |||||||||
---|---|---|---|---|---|---|---|---|---|
chr | start | end | strand | Gene | exon type | effect | FUS | TDP-43 | U2AF65 |
chr4 | 134481443 | 134481943 | + | D4Wsu53e | Cassette | ![]() |
89 | 13 | 98 |
chr16 | 94614470 | 94614970 | + | Ttc3 | Cassette | ![]() |
24 | 0 | 19 |
chr6 | 38515406 | 38515906 | + | Luc7l2 | Cassette | ![]() |
19 | 2 | 22 |
chr10 | 5917827 | 5918327 | + | Rmnd1 | Cassette | ![]() |
17 | 2 | 3 |
chr8 | 107812815 | 107813315 | − | 4931428F04Rik | Cassette | ![]() |
9 | 0 | 9 |
chr11 | 104179222 | 104179722 | + | Mapt | Cassette | ![]() |
7 | 2 | 9 |
chr5 | 108497932 | 108498432 | + | Mtf2 | Cassette | ![]() |
5 | 0 | 7 |
chr1 | 183841540 | 183842040 | − | Enah | Cassette | ![]() |
4 | 0 | 21 |
chrX | 132277732 | 132278232 | + | Gprasp1 | Cassette | ![]() |
2 | 0 | 7 |
chr15 | 3941706 | 3942206 | − | AW549877 | Bleeding | ![]() |
9 | 5 | 18 |
chrX | 132376016 | 132376516 | + | Gprasp1 | Bleeding | ![]() |
3 | 0 | 0 |
chr11 | 4979238 | 4979738 | − | Ewsr1 | Intron | ![]() |
60 | 3 | 31 |
chr1 | 58477677 | 58478177 | − | Clk1 | Intron | ![]() |
9 | 0 | 40 |
chr9 | 103258106 | 103258606 | − | Cdv3 | 3′ variable | ![]() |
3 | 0 | 3 |
chr1 | 164603984 | 164604484 | − | Bat2d | 5′ variable | ![]() |
8 | 0 | 12 |
chr12 | 71367229 | 71367729 | − | Trim9 | Terminal | ![]() |
1 | 0 | 8 |
chr18 | 38456210 | 38456710 | + | Rnf14 | Promoter | ![]() |
2 | 0 | 0 |