Table 1.

Cancers associated with high-risk HPV infection and with HPV16 and 18 infection.

			Number of cancers
Site	Attributable to hrHPV	Of which HPV16/18	Total	Attributable to hrHPV	Attributable to HPV16/18
Cervix	100% 2	71% 4	529,500 19	529,500	375,945
Penis	47% 9	74% 9	26,300 23	12,361	9,098
Vulva	40% 95	93% 95	30,000 23	12,000	11,100
Vagina	70% 95	93% 95	15,000 23	10,500	9,750
Anus (female)	84% 95	94% 95	15,900 23	13,356	12,561
Anus (male)	84% 95	94% 95	14,5900 23	12,180	11,455
Oro-pharynx (female)	19% 96†	89% 13	12,900 97	2,394	2,138
Oro-pharynx (male)	19% 96†	89% 13	48,900 97	9,291	8,299
All sites (females)	9.4%	6.8%	6,044,710	567,750	411,494
All sites (males)	0.5%	0.4%	6,617,844	33,832	28,852
All sites (both sexes)	4.8%	3.5%	12,662,554	601,582	440,346

hrHPV: high-risk human papillomavirus

^†weighted average of region-specific estimates (derived from de Martel et al, 2012)⁹⁶