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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Acta Biomater. 2012 Jun 28;8(10):3552–3560. doi: 10.1016/j.actbio.2012.06.031

Figure 2. Effect of siRNA-PEI-loaded MPs on cytokine levels.

Figure 2

Anti-FcγRIII-siRNA-PEI-loaded PLGA MPs reduced protein-level expression of inflammatory cytokines interleukin-6 (IL-6) and IL-1β. Protein was extracted from retrodiscal TMJ tissue on day 9 of the experiment, and then interleukin levels were measured via ELISAs. Values for each group are expressed relative to the total protein content; data points represent the mean ± standard error of the mean for n = 6 rats. In each panel, groups marked with * differ significantly from all other groups, while pairs of groups marked with ** or *** differ significantly from all other groups but not each other (p < 0.05).

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