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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Acta Biomater. 2012 Jun 28;8(10):3552–3560. doi: 10.1016/j.actbio.2012.06.031

Figure 5. Size of polyplexes released from PLGA MPs over time.

Figure 5

Although the average diameters of the polyplexes for each siRNA type were similar when considering all timepoints together (135 ± 50 nm for siRNA1-PEI and 117 ± 50 nm for siRNA2-PEI), the size of the two polyplex types at each timepoint differed significantly (p < 0.05), based on repeated measures analysis of variance. Data are presented as the mean ± standard deviation for (n = 4) samples at each timepoint. Error bars are included for all data points, though they are too small to resolve in some cases. The white-filled data points at 0 nm correspond to groups with no detectable polyplexes (e.g., only free PEI was detected for siRNA2-PEI on day 3, as shown in Figure 6).

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