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. Author manuscript; available in PMC: 2013 Oct 1.
Published in final edited form as: Cytokine. 2012 Jun 15;60(1):302–308. doi: 10.1016/j.cyto.2012.05.017

Figure 4. Receiver Operator Characteristic (ROC) curves for (a) high TCD velocity and (b) stroke development on plasma levels BDNF, PDGF-AA and -AB/BB.

Figure 4

The Area Under the Curve (AUC) was 0.84, and 0.87 for BDNF and PDGF-AA respectively in Fig. 4a. While the AUC was 0.71, and 0.91 respectively for BDNF and PDGF-AA in Fig. 4b. It shows that although BDNF and PDGF AA are sensitive in detecting presence of abnormally high cerebral blood flow velocity, only PDGF AA was a useful biomarker of risk for stroke development in SCA subjects (AUC = 0.91). The AUC for PDGF-AB/BB was not significant in both situation. TCD = trans-cranial Doppler.