Table 1.
Characteristic of subjects and their distribution based on the defined groups. There was no significant difference in age and gender distribution among groups. Except in height, SCA subjects were significantly different from controls (p<0.001). There was no significant difference between the SNTCD and SATCD except in reticulocytes percent (p=0.009) and hemoglobin level (p=0.004).
Characteristics | Controls | SNTCD | SATCD |
---|---|---|---|
Number | 7 | 13 | 19 |
Gender (m/f) a | 4/3 | 3/10 | 9/10 |
Age (y) a | 9.6 ± 1.7 | 8.8 ± 2.3 | 8.1 ± 3.1 |
Height (m) a | 1.3 ± 0.2 | 1.3 ± 0.1 | 1.3 ± 0.2 |
Weight (kg) a | 40.4 ± 7.9 | 24.5 ± 4.5 | 24.5 ± 7.0 |
BMI (kg/m2) a | 22.9 ± 6.8 | 14.8 ± 0.9 | 15.7 ± 1.5 |
Platelet count (×1000/μL) a | 250 ± 39 | 452 ± 169 | 385 ± 67 |
Reticulocytes percent (%) a | 1.0 ± 0.5 | 9.2 ± 3.0 | 12.9 ± 3.5 |
White Blood Cells count (×1000/μL) a | 5.1 ± 1.8 | 10.8 ± 2.6 | 11.0 ± 2.6 |
Hemoglobin level (g/dL) a | 12.4 ± 0.6 | 8.6 ± 0.8 | 7.5 ± 0.8 |
Values are means±SD. SNTCD = sickle cell anemia subject with normal TCD, SATCD = Sickle cell anemia subject with abnormal or high TCD, TCD = Transcranial Doppler