Table VII.

First Series of Assessments: Deposition Profile Data (microgram per actuation) from DPI Inhaler “A” for the ACI at Different Sample Durations

Duration	1 s		2 s		4 s		8 s		16 s		Controla
Location	Mean	CofV	Mean	CofV	Mean	CofV	Mean	CofV	Mean	CofV
I.P.	231.0	2.3	215.6	2.9	202.3	1.5	199.1	6.5	217.7	5.0	181.2
P.S.	341.9	5.4	371.8	2.9	376.9	4.6	414.9	4.2	387.9	2.5	413.8
Stage 1	51.6	0.4	53.4	10.8	51.3	1.5	52.3	5.6	54.1	2.0	57.0
Stage 2	48.4	5.1	48.4	16.0	44.8	5.2	42.8	9.5	47.5	6.7	49.4
Stage 3	57.0	9.5	54.2	17.6	47.0	7.9	42.6	13.5	51.2	5.7	54.7
Stage 4	18.5	16.3	16.1	19.8	13.6	14.0	11.4	18.4	14.6	10.4	15.5
Stage 5	4.3	21.3	3.3	20.4	2.8	17.9	2.2	23.7	2.8	12.4	3.0
Stage 6	0.8	19.9	0.6	27.0	0.5	10.8	0.5	44.6	0.6	10.2	0.4
Stage 7	0.4	53.3	0.4	50.0	0.3	45.8	0.4	43.3	0.4	13.3	0.2
Filter	0.2	69.3	0.1	43.3	0.1	43.3	0.1	43.3	0.2	34.6	0.1

^aSeven actuations from inhaler in accordance with standardized procedure in effect at GSK plc