Table IV.
Tumor Weight and Tumor Inhibitory Rate After i.v. Administration of F-Lip, C-Lip, and C-Inj in S180 Tumor-Bearing Mice (mean ± SD, n = 11)
| Groups | Dose (mg/kg) | Weight of tumor (g) | Tumor inhibitory rate (%) |
|---|---|---|---|
| Blank | / | 0.97 ± 0.39 | 0 |
| F-Lip | 20 | 0.37 ± 0.22** | 61.84 |
| 10 | 0.63 ± 0.38* | 35.05 | |
| 5 | 0.70 ± 0.28* | 27.83 | |
| C-Lip | 20 | 0.43 ± 0.38** | 55.64 |
| 10 | 0.65 ± 0.49* | 32.72 | |
| 5 | 0.72 ± 0.36 | 25.73 | |
| C-Inj | 40 | 0.49 ± 0.25* | 48.48 |
| 20 | 0.63 ± 0.25 | 35.05 | |
| 10 | 0.69 ± 0.46 | 28.87 |
F-Lip CPT-11-loaded folate-targeted liposome, C-Lip CPT-11-loaded liposome, C-Inj CPT-11 injection
*p > 0.05 vs. control group (the blank); **p > 0.01 vs. control group (the blank)