Table V.
Thymus Index and Spleen Index After i.v. Administration of F-Lip, C-Lip, and C-Inj in S180 Tumor-Bearing Mice (Mean ± SD, n = 11)
Groups | Dose (mg/kg) | Thymus index (g/kg) | Spleen index (g/kg) |
---|---|---|---|
Blank | / | 1.27 ± 0.56 | 14.41 ± 4.58 |
20 | 0.68 ± 0.25* | 12.30 ± 2.82 | |
F-Lip | 10 | 0.70 ± 0.50 | 14.84 ± 3.61 |
5 | 1.01 ± 0.15 | 16.39 ± 4.23 | |
20 | 0.51 ± 0.25** | 12.83 ± 3.56 | |
C-Lip | 10 | 0.86 ± 0.21** | 14.78 ± 2.10 |
5 | 0.65 ± 0.50** | 16.09 ± 3.99 | |
40 | 0.70 ± 0.35** | 10.34 ± 2.92* | |
C-Inj | 20 | 0.75 ± 0.44** | 14.82 ± 3.69 |
10 | 0.65 ± 0.49** | 11.53 ± 2.30* |
F-Lip CPT-11-loaded folate-targeted liposome, C-Lip CPT-11-loaded liposome, C-Inj CPT-11 injection
*p > 0.05 vs. control group (the blank); **p > 0.01 vs. control group (the blank)