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. 2012 May 26;13(3):802–810. doi: 10.1208/s12249-012-9776-5

Table V.

Thymus Index and Spleen Index After i.v. Administration of F-Lip, C-Lip, and C-Inj in S180 Tumor-Bearing Mice (Mean ± SD, n = 11)

Groups Dose (mg/kg) Thymus index (g/kg) Spleen index (g/kg)
Blank / 1.27 ± 0.56 14.41 ± 4.58
20 0.68 ± 0.25* 12.30 ± 2.82
F-Lip 10 0.70 ± 0.50 14.84 ± 3.61
5 1.01 ± 0.15 16.39 ± 4.23
20 0.51 ± 0.25** 12.83 ± 3.56
C-Lip 10 0.86 ± 0.21** 14.78 ± 2.10
5 0.65 ± 0.50** 16.09 ± 3.99
40 0.70 ± 0.35** 10.34 ± 2.92*
C-Inj 20 0.75 ± 0.44** 14.82 ± 3.69
10 0.65 ± 0.49** 11.53 ± 2.30*

F-Lip CPT-11-loaded folate-targeted liposome, C-Lip CPT-11-loaded liposome, C-Inj CPT-11 injection

*p > 0.05 vs. control group (the blank); **p > 0.01 vs. control group (the blank)