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. 2012 May 15;13(3):772–784. doi: 10.1208/s12249-012-9801-8

Table I.

Classification of Drugs Based on Their Glass Formation Ability (Adapted from (33))

Class Behaviora Examples
Class 1 A Always crystallize on cooling Atenolol, felbinac
B Amorphous on quench cooling Griseofulvin, carbamazepine
Class 2 Cooling—no crystallization; heating—crystallization Acetaminophen, cinnarizine
Class 3 Cooling and heating—no crystallization Piroxicam, ketoconazole, indomethacin, ursodiol

aCooled at 20°C/min, heated at 10°C/min in a DSC