Table 4.

Parameters with significant partial correlation with FFbH changes at month 12 in the regression analysis set

Regression model FFbH, N  = 2,625	Model values
		Constant	Total R²	P-value
		36.647	0.205	<0.001

Variable	Value	Beta-weight	Partial r 2	P-value
Positive predictors for increase in functional capacity
Employment	1 = yes, 0 = no	3.078	0.023	<0.001
Gender	1 = male, 0 = female	3.160	0.005	<0.001
COX-2 inhibitors	1 = yes, 0 = no	2.892	0.005	<0.001
ESR	Continuous	0.047	0.004	<0.001
Patient global assessment	Number (0–10)	0.653	0.003	<0.001
Negative predictors for increase in functional capacity
Baseline FFbHa	Continuous (0–100% points)	−0.317	0.126	<0.001
Disease duration	Continuous	−0.171	0.017	<0.001
Joint replacement	1 = yes, 0 = no	−4.277	0.008	<0.001
Age (years)	Continuous	−0.123	0.005	<0.001
Previous biologics	Number (0, 1, 2, 3, 4)	−2.149	0.005	<0.001
BMI (kg/m²)	Continuous	−0.258	0.005	<0.001

BMI body mass index, COX-2 cyclo-oxygenase 2, ESR erythrocyte sedimentation rate, FFbH Funktionsfragebogen Hannover functional capacity questionnaire, MTX methotrexate

^aHigh FFbH values indicate high functional capacity (low impairment)