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Immunohistochemical stains of lung adenocarcinoma cases. (A) and (B) E746 and L858R EGFR mutation-specific antibodies show a positive staining at tumor cells (A, E746 mutation-specific antibody, × 200; B, L858R mutation-specific antibody, × 400). (C) In a case of adenocarcinoma showing signet ring cell feature, ALK positivity is present at tumor cells (ALK, × 400).
