Table A3.

Statistics and input parameters for the multiple regression model with efficient prediction of silencing activities on the filtered database (n = 10735 oligonucleotides).

Parameter	Coefficient	P-value
Intercept	−69.95	2.442 × 10−120
ΔG	−4.712	1.3659 × 10−91
ΔG2	−0.1204	9.0266 × 10−90
ΔG3	−0.001024	4.7275 × 10−91
ΔG1	0.4039	0.00539301
A1	1.034	1.3622 × 10−05
A2	0.8842	9.3786 × 10−08
A3	0.8345	0
A4	0.4935	4.6521 × 10−12
A5	0.6545	0
A11	0.3861	7.211 × 10−08
Al2	0.5024	4.3667 × 10−11
A13	1.004	0
A19	−0.5374	3.2157 × 10−14
A20	−1.236	4.1586 × 10−72
A22	0.2766	0.00019726
G6	−0.3111	3.333 × 10−05
G7	−0.2761	0.0003269
G9	−0.3142	1.1835 × 10−05
G10	−0.851	5.2291 × 10−23
G14	−0.4395	4.8444 × 10−09
G17	−0.2894	9.3124 × 10−05
G18	−0.3296	3.4827 × 10−06
G19	−0.1936	0.00914666
G21	0.3931	3.7168 × 10−08
C4	−0.2648	0.00034025
C5	−0.3841	2.1001 × 10−07
C7	−0.5525	2.7151 × 10−13
C8	−0.2283	0.00124906
C10	−0.8191	5.6655 × 10−22
C11	−0.2768	0.00017918
C13	−0.3399	7.0633 × 10−05
U1	2.455	0
U2	0.8241	3.3472 × 10−06
U3	0.7619	0
U6	0.6131	0
U10	−0.402	6.0954 × 10−07
U12	0.5706	7.5273 × 10−14
U13	0.7699	0
U14	0.7817	0
U17	0.3807	8.677 × 10−08
U22	0.303	3.6557 × 10−05