Table 1 . r2 results for hypergeometric-theoretical P values, hypergeometric-empirical P values, and r2 difference between the hypergeometric-theoretical P values and the hypergeometric-empirical P values.
Hypergeometric r2 | Empirical r2 | Difference r2 | |
---|---|---|---|
Genes | 0.014 | 0.039 | 0.225 |
SNPs | 0.061 | 0.058 | 0.431 |
SNP-gene ratio | 0.056 | 0.013 | 0.082 |
The predictive variables used were functions of the number of genes, the number of SNPs, or the SNP-gene ratio in the pathways. These predictors were categorized into groups representing the size of the pathway (i.e., amount of genes/SNPs/SNP-gene ratio on each pathway).