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. 2012 Sep 1;2(9):1067–1075. doi: 10.1534/g3.112.002618

Table 1 . r2 results for hypergeometric-theoretical P values, hypergeometric-empirical P values, and r2 difference between the hypergeometric-theoretical P values and the hypergeometric-empirical P values.

Hypergeometric r2 Empirical r2 Difference r2
Genes 0.014 0.039 0.225
SNPs 0.061 0.058 0.431
SNP-gene ratio 0.056 0.013 0.082

The predictive variables used were functions of the number of genes, the number of SNPs, or the SNP-gene ratio in the pathways. These predictors were categorized into groups representing the size of the pathway (i.e., amount of genes/SNPs/SNP-gene ratio on each pathway).