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. 2012 Sep 1;2(9):1077–1084. doi: 10.1534/g3.112.003095

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Copyright © 2012 Sugimoto, Sugimoto

This is an open-access article distributed under the terms of the Creative Commons Attribution Unported License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Susceptibility to mastitis is linked to IGF1R through FEZL. (A) F-statistic profile on BTA21 according to QTL express. (B) Schematic representation of genes (black) and microsatellite markers (blue dot) located in the candidate region. (C) Average expression level ± SE of genes located in the candidate region. 12GFEZL and 13GFEZL were transfected with the respective FEZL. P values were calculated by Student’s t-test. (D) Schematic representation of bovine IGF1R carrying polymorphisms on its 5UTR regions. The vertical and double lines indicate exons and the 5UTR region, respectively. (E) Average luciferase activity ± SE of IGF1R in COS7 cells transfected with FEZL. P values were calculated by Student’s t-test.