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. 2012 Sep 1;2(9):977–986. doi: 10.1534/g3.112.003061

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Copyright © 2012 O'Bleness et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution Unported License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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(A) Consensus tree of evolutionary relationships of 429 DUF1220 sequences. The evolutionary history was inferred using the Minimum Evolution method with the consensus tree inferred from five optimal trees. Species covered by the tree are color coded. The different types of DUF1220 clades are bracketed. (B) Gene organization of the three distinct types of NBPF genes. Top: Nonprimate mammal NBPF organization (NBPFs 4, 6, and 7). Middle: Typical primate NBPF organization (NBPFs 1, 3, 9, 11, 13, 24, 15, 16. and 23). Bottom: HLS NBPF organization (NBPFs 8, 10, 12, 25, 14, and 20).