Table 4. Pairwise comparisons of the Dat21–230–AcCoA structure with five N-acetyltransferases by the iSARST server [32].
AAC (6′)-li, aminoglycoside 6′-N-acetyltransferase type li; GNA1, glucosamine-6-phosphate N-acetyltransferase 1; HPA2, histone acetyltransferase 2; TTR, tabtoxin-resistance protein.
| N-acetyltransferase | Aligned residues | Identity* | Similarity† | RMSD for the Cα carbons (Å) | Structure diversity‡ iSARST score | PDB code |
|---|---|---|---|---|---|---|
| SNAT | 125 | 12% (20/166) | 23% (38/166) | 1.89 | 3.47 | 1CJW |
| TTR | 128 | 8.4% (14/166) | 26% (43/166) | 2.33 | 4.16 | 1GHE |
| AAC (6′)-li | 120 | 12% (22/181) | 25% (45/181) | 2.20 | 4.58 | 1B87 |
| HPA2 | 127 | 15% (22/150) | 29% (44/150) | 3.41 | 5.75 | 1QSM |
| GNA1 | 126 | 15% (23/154) | 31% (47/154) | 3.82 | 6.63 | 1I12 |
*Values in parentheses: (number of identical residues in the aligned regions/inquiry protein sequence length)×100.
†Values in parentheses: (number of conservatively exchanged residues in the aligned regions/inquiry protein sequence length)×100.
‡Structure diversity: RMSD/(number of residues in the aligned sequence/total number of residues in the shorter-length protein)1.5.