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. 2012 Aug 14;5:77–87. doi: 10.2147/JIR.S34225

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© 2012 Vega-Carrascal et al, publisher and licensee Dove Medical Press Ltd.

This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.

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The different types of galectins in humans.

Notes: Human galectins have been classified according to their structure into prototypical, chimeric, and tandem repeat. The oval domain represents the carbohydrate recognition domain (CDR). Prototypical galectins such as galectin-1 contain only one type of CDR, chimeric galectin-3 contains a single CDR attached to a long polypeptide chain, whereas tandem-repeat galectins such as galectin-9 consist of two different CDRs connected by an inter-domain polypeptide linker.