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. Author manuscript; available in PMC: 2012 Aug 29.
Published in final edited form as: J Med Chem. 2009 Mar 12;52(5):1450–1458. doi: 10.1021/jm8014525

Figure 2. Difference in potency distribution between lucPpy and Ultra-Glo luciferase formulations.

Figure 2

Active compounds from the previous lucPpy qHTS and the Ultra-Glo luciferase qHTS were compared and the ΔLogAC50 values were calculated. Negative ΔLogAC50 values represent compounds that were less potent in the Ultra-Glo luciferase compared to the lucPpy qHTS, while positive ΔLogAC50 values represent compounds that were more potent in the Ultra-Glo luciferase compared to the lucPpy qHTS.