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. Author manuscript; available in PMC: 2012 Aug 29.
Published in final edited form as: J Med Chem. 2009 Mar 12;52(5):1450–1458. doi: 10.1021/jm8014525

Table 2.

Analysis of qHTS. Numbers in parenthesis represent the % of inhibitors found for this CRC class in the lucPpy qHTS

Curve Classification
IC50 (μM) 1a 1b 2a 2b 3 Total
< 0.1 0 0 0 0 0 0
0.1 to 1 3 11 0 0 0 14
1 to 10 40 0 139 335 159 673
10 to 100 0 0 93 502 254 849

Total per classification 43 11 232 837 413 1,536
% of Library 0.02,(0.29) 0.01,(0.19) 0.12,(0.34) 0.42,(1.79) 0.21,(0.59) 0.78,(3.19)