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(A) Immunohistochemistry against CD68 (a macrophage marker) reveals that in normal pregnancy macrophages are present near the trophoblast. In case of spontaneous abortions the number of macrophages is increased; additionally it seems that they are significantly infiltrating the trophoblast. (B) Dual immunofluorescence against CD69 and FasL revealed that the latter’s expression is significantly increased in macrophages involved in spontaneous miscarriages.
