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. 2012 Jul 24;13(7):9298–9331. doi: 10.3390/ijms13079298

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© 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.

This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).

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Mesenchymal stem cells can induce neuron recovery in multiple sclerosis via a mechanism that stimulates oligodendrogenesis and decreases the numbers of Th1 and Th17 cells and their secretion of inflammatory cytokines while increasing the numbers of Th2 and Treg cells and their secretion of anti-inflammatory cytokines.