(A) The conditions for vesicle formation, the hydrodynamic diameter, and the size distribution of the corresponding PBMA75-b-PNAM51 vesicle and its cytotoxicity profile in aqueous solution. (B) Transmission electron microscopy image of the morphology of the well-defined vesicles with hydrophilic hollow inner space and hydrophobic bilayer and structural confirmation by nuclear magnetic resonance spectroscopy.
Abbreviations: PBMA75-b-PNAM51, poly(n-butyl methacrylate)x-b-poly(N-acryloylmorpholine)y, with hydrophobic to hydrophilic block ratio regulated at 73/51; PEI, polyethylenimine.