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The scheme illustrated complexation between carrier (polyethylenimine [PEI] and vesicles) and plasmid DNA (pDNA). (A) shows the hydrodynamic and kinetic conditions for well-defined vesicle formation, pDNA condensing, and the properties of the corresponding stealth polyplex; (B) shows the polyplex formation by cationic PEI with pDNA and the corresponding size and surface properties of the polyplex.
Note: The dimensions of the drawn polyplex do not reflect its real size.
