FIGURE 2. Putative GLUT1 homology modeled structure.
adapted from the GlpT homology model (508) and analyzed using the software program VMD 1.8.5 (© University of Illinois 2006). GLUT1 coordinates were obtained from the RCSB Protein Data Bank (entry No. 1SUK). A. GLUT1 viewed as a membrane spanning protein along the bilayer plane. The limits of the bilayer are indicated by the dashed lines. Membrane spanning helices (TMs) are color coded as in Figure 1. B, putative helix packing arrangement viewed from the cytoplasmic surface. TMs are numbered and colored as in 2A. Cytoplasmic and exofacial loops are indicated by solid and dashed linesrespectively. A scale bar (5 nm) is indicated.