Table 1.
Summary of the effects of zinc in pathophsiology and treatment of depression
Type of Study | Zinc Concentration |
---|---|
Human studies: | |
Depression | ⇓ serum (35) |
Chronic depression (women) | ⇓ serum (45) |
Postpartum depression | ⇓ serum (46) |
Animal tests/models: | |
Depression+zinc treatment | ⇑ brain (synaptic hippocampal zinc) (47) |
Forced swim test with Zinc treatment+antidepressant treatment | ⇓ immobility (44) |
⇓ Decrease ⇑ Increase