Fig. 5.

(×400 immunostained Bcl-2) demonstrates partial cancerization of a lobule; of interest, the cells associated with the cancerization are stained strongly with Bcl-2 (gray arrows). Panel B (×400, immunostained Bcl-2) demonstrates a small lobular area with cancerization of the ductolobular unit. Note lymphocytes surrounding the ductolobular units are staining strongly with Bcl-2 as would be expected; however the remaining basal cells staining with Bcl-2 (gray arrows) are reduced to only a partial layer and there is only weak staining of the luminal cells.