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. 2012 Aug 8;32(32):11067–11081. doi: 10.1523/JNEUROSCI.5604-11.2012

Figure 5.

Figure 5.

Decreased AMPA conductance but increased NMDA conductance in stg RTN eEPSCs. Representative examples of eEPSCs from several holding potentials (−60, −30, 30, and 40 mV) at different timescales in WT (Ai, Aii) and stg (Bi, Bii) RTN cells with the respective I–V curves for AMPAR (black squares) and NMDAR (white squares) components on the right (Aiii, Biii). AMPAR currents (Ci) and conductance (Cii) are reduced in stg cells (white squares) compared with WT (black squares). Ciii, Box-and-whisker plot of mean AMPAR conductance. NMDAR currents (Di) and conductance (Dii) are increased in stg cells (white squares) compared with WT (black squares). Diii, Box-and-whisker plot of maximum NMDAR conductance (mean conductance at 20–40 mV) in WT and stg RTN cells. E, Box-and-whisker plot showing that the NMDAR/AMPAR ratio at 20–40 mV is increased in stg cells. *p < 0.05, ***p < 0.0005.