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Dose dependent activity of isolated ursolic acid or fraction-A and acyclovir on HSV-1 [A] and HSV-2 [B]. Different concentrations of fraction A, isolated ursolic acid or acyclovir (2.5-15 μg/ml) were added to HSV-1 and HSV-2 (black, grey and white bars) infected Vero cells after 1 h of infection. Inhibition percentage was evaluated by MTT assay after 3 days of incubation at 37°C. Each bar represents the mean ± S.E.M of three independent experiments.
