Table 5. Kinetic constants of mAb 8E10 binding to BoNT/A/B/E/F-Hc.
Serotype | koff (M-1 S-1) | kon (S-1) | KD (M) |
BoNT A | 1.077E−4 | 1.442E+4 | 7.468E−9 |
BoNT B | 3.270E−5 | 1.261E+4 | 2.592E−9 |
BoNT E | 6.209E−5 | 1.189E+4 | 5.223E−9 |
BoNT F | 1.030E−4 | 1.339E+4 | 7.690E−9 |